Doctor Octopus is once again in search of more power to defeat Spider-Man, and this time he finds a sidekick in a genius kid inventor.

Still yearning to be seen as heroes, Wolf, Shark, Snake, and Piranha set out to rescue ten thousand chickens from a high-tech cage farm--but one unexpected problem is Mr. Snake himself, also known as "The Chicken Swallower."

" A MYSTERIOUS DOORWAY! (Sure, it's in the grossest restaurant in the world, but that doesn't make it less mysterious. OK?) Behold! What lies beyond?! An evil centipede? An alternate universe? A few decent explanation? VRRRING! NING! NING! NING! Hey, was that a chainsaw?! Let's see if you can and run at the same time...GO! It's the BAD GUYS" next adventure!" -- 

"Pop quiz! You are on the roof of a skyscraper. Every floor of that building has nasty things that just don't like you. And you really need to get to the basement. Whaddaya do?! (And no, you can't just join the B-Team and fly away in their glamorous new spaceship.) Think quick, chico, because the multiverse is getting worse!"--

Captain America's nemesis, the Red Skull, has been murdered and Cap must find his killer. Plus, he has to retrieve the Skull's last project, a Cosmic Cube that can alter reality, and stop a group of the Skull's followers from setting off bombs in Paris, London, and Manhattan.